The number and relative age of siblings is related to the risk of cardiovascular events

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First-born children have a lower risk of cardiovascular events such as heart attacks and strokes than siblings born later, but people who are part of a large family with many siblings have a higher risk of these events, suggests the results study of the population in Sweden, published in the online journal BMJ Open.

It is well known that —Parents ‘and grandparents’ health— has an impact on a person’s health, including the risk of cardiovascular events, but there is now a growing interest in what influence a person’s immediate family composition can have. the number and age of the brothers. to own.

The authors accessed data on 1.36 million men and 1.32 million women born between 1932 and 1960 and aged between 30 and 58 in 1990 from the Swedish Register of Multiple Generations. Data on fatal and non-fatal cardiovascular and coronary events over the next 25 years were retrieved from national records.

Analysis of the data showed that the firstborns had one of non-fatal cardiovascular and coronary events than siblings born later. Firstborn men had a higher risk of death than second and third siblings, while firstborn women had a higher risk of death than second born siblings, but just like other siblings.

When the size was observed, compared with men without siblings, men with one or two siblings had a lower risk of cardiovascular events, while those with four or more siblings had a higher risk.

Similarly, compared to men without siblings, men with more than one sibling had a lower risk of death, while those with three or more siblings had a higher risk of coronary events.

A similar pattern was observed in women. Compared to those who have no siblings, with three or more siblings had an increased risk of cardiovascular events, while those with two or more siblings had a higher risk of coronary events. Women with one or more siblings had a lower risk of death.

This is an observational study and, as such, cannot determine the cause. The authors also highlight some limitations, such as the fact that Swedish records do not include information on diagnostic procedures and that there are no data on lifestyle factors, such as body mass index, smoking and diet.

Despite this, , obesity, diabetes, (COPD) and alcoholism and related liver disorders. They also point out that some of their findings conflict with those of previous studies.

The authors note that because family support policies and the number of children currently vary widely across countries, their findings could have public health implications.

“More research is needed to understand the links between “It is said that” it is aimed at future research to find biological or social mechanisms that relate the state of being born to a lower risk of cardiovascular disease, as indicated by our observational results. ”


Preemis with the highest risk of mortality in adulthood


More information:
Rank of siblings and number of siblings in relation to cardiovascular disease and risk of mortality: a cohort study at the national level, BMJ Open (2021). DOI: 10.1136 / bmjopen-2020-042881

Citation: The number and relative age of siblings is related to the risk of cardiovascular events (2021, May 25) recovered on May 25, 2021 at https://medicalxpress.com/news/2021-05-relative- age-siblings-linked-cardiovascular.html

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