(HealthDay): Supplementation with a higher dose of docosahexaenoic acid (DHA) compared to the standard prenatal dose during the second half of pregnancy is associated with a lower rate of early preterm birth, according to a published study online May 17 at Clinical Medicine.
Susan E. Carlson, Ph.D., of the University of Kansas in Kansas City, and colleagues randomly assigned women with individual pregnancies and 12 to 20 weeks of gestation to DHA supplementation (1,000 mg: 576 women). ; 200 mg: 524 women).
The researchers found that the highest dose of DHA was associated with a lower premature birth rate (1.7 versus 2.4%; later probability). [pp] = 0.81). Results were even stronger among participants with a low DHA status at enrollment (2.0 versus 4.1 percent; pp = 0.93). No effect of dose was observed among participants with elevated DHA status at enrollment (1,000 mg: 1.4%; 200 mg: 1.1%; pp = 0.57). There were fewer serious adverse events (maternal: chorioamnionitis, premature rupture of membranes, pyelonephritis; neonatal: eating, genitourinary and neurological problems; all pp> 0.90) associated with the highest dose.
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Citation: Higher DHA Dose During Pregnancy Linked to Fewer Premature Births (2021, June 21) Retrieved June 21, 2021 at https://medicalxpress.com/news/2021-06-higher-dose-dha -pregnancy-tied-early. html
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