Sleep disorders are associated with an increased risk of dementia in patients with TBI


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Preliminary results a to study of more than 700,000 patients with traumatic brain injury (TBI) show that people with sleep disorder had a higher risk of developing dementia.

The results show that during an average follow-up period of more than four years, patients with TBI with a diagnosed sleep disorder were 25% more likely to develop dementia. The results were similar when stratified by sex: having a sleep disorder was associated with a 25.5% increase in the risk of incident dementia in males with TBI and a 23.4% increase in the risk of developing dementia in women with TBI.

“The novelty of our study is the confirmation of the association of sleep disorders with incident dementia in both men and women. , regardless of other known risks of dementia, ”said lead author and lead researcher Dr. Tatyana Mollayeva, a scientist affiliated with the Milan Research Institute, the Toronto Rehabilitation Institute research group and one of the leading institutes Mollayeva is part of the acquired team of brain injuries and KITE society. She is also an adjunct professor at the Dalla Lana School of Public Health. “We are also the first to report on the risks that sleep disorders and other factors represent separately for men and patients with TBI “.

The retrospective study included a province-wide cohort of all adult patients who were free of dementia when they were admitted to the emergency department or acute care hospital diagnosed with TBI between May 2003 and April 2013. The sample total included 712,708 patients with TBI of all severities. Theirs he was 44 years old and 59% were men.

Over an average follow-up period of 52 months, 32,834 patients (or 4.6%) developed dementia. Controls analyzed by age, sex, , severity of injuries and known risks of comorbidity.

“Strong links with the incidence of in both sexes suggest the need for more specific awareness about sleep disorders in patients with TBI, ”Mollayeva said.

The research summary was recently published in a online supplement of the magazine Sleep and will be presented as an oral presentation on June 13 during Virtual SLEEP 2021.

Link between sleep apnea and increased risk of dementia

More information:
Tatyana Mollayeva et al, 794 Contribution of sleep disorders to the incidence of dementia after traumatic brain injury: a ten-year retrospective cohort study, Sleep (2021). DOI: 10.1093 / sleep / zsab072.791

Newspaper information:

Citation: Sleep Disorders Associated with Increased Risk of Dementia in Patients with TBI (2021, June 8) Retrieved June 8, 2021 at dementia-patients-tbi.html

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