According to a small study by UC San Francisco, no messenger RNA vaccines against COVID-19 were detected in human milk, providing early evidence that the vaccine mRNA is not transferred to the baby.
The study, which analyzed the breast milk of seven women after receiving mRNA vaccines and found no trace of it vaccine, provides the first direct data on vaccine safety during breastfeeding and could alleviate concerns among those who have refused vaccination or stopped giving their infant due to concern that vaccination may alter human milk. The paper appears in JAMA Pediatrics.
Research has shown that mRNA vaccines inhibit the transmission of the virus that causes COVID-19. The study looked at Pfizer and Moderna vaccines, which contain mRNA.
The World Health Organization recommends vaccinating people who are breastfeeding, and the Academy of Breastfeeding Medicine has said there is little risk that vaccine nanoparticles or mRNA will enter or be transferred to breast tissue. milk, which could theoretically affect infant immunity.
“The results reinforce current recommendations that mRNA vaccines are safe during lactation and that infants receiving the COVID vaccine should not stop breastfeeding,” said the corresponding author, Stephanie L. Gaw, MD, Ph.D., Assistant Professor of Fetal Medicine at UCSF.
“We did not detect vaccine-associated mRNA in any of the milk samples tested,” said lead author Yarden Golan, Ph.D., a UCSF postdoctoral fellow. “These findings provide experimental evidence on the safety of mRNA-based vaccine use during lactation.”
The study was conducted from December 2020 to February 2021. The average age of mothers was 37.8 years and their children were between one and three years old. Milk samples were collected before vaccination and at different times up to 48 hours after vaccination.
The researchers found that none of the samples showed detectable levels of vaccine mRNA in any component of the milk.
The authors noted that the study was limited by small sample size and he said it further clinical data larger populations were needed to better estimate the effect of vaccines on breastfeeding outcomes.
Yarden Golan et al, Evaluation of Messenger RNA From COVID-19 BTN162b2 and mRNA-1273 Vaccines in Human Milk, JAMA Pediatrics (2021). DOI: 10.1001 / jamapediatrics.2021.1929
University of California, San Francisco
Citation: No sign of COVID-19 vaccine in breast milk (2021, July 16) recovered on July 17, 2021 at https://medicalxpress.com/news/2021-07-covid-vaccine-breast.html
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