Multiple long-term physical health problems increase the risk of depression later in life

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According to new research, middle-aged people in the UK with at least two long-term physical health conditions have a higher risk of developing depression or anxiety later in life compared to those who do not have any or only one condition. long-term physical health. King’s College London.

Published in The Lancet Regional Health – Europe and funded in part by the Maudsley Biomedical Research Center of the National Institute for Health Research (NIHR), the study identified that people with multiple they were more likely to develop depression and anxiety later. This has potential implications for future health services if the Covid-19 pandemic causes an increase in long-term respiratory problems. The study confirms the importance of integrating the mindset early care support plans for those with multiple physical health conditions.

This is the first study of this scale to assess how specific patterns of physical health conditions are associated with common mental health conditions later in life, including anxiety.

Lead author Dr Amy Ronaldson of the Institute of Psychiatry, Psychology and Neuroscience (IoPPN) at King’s College London said: “Our large-scale analysis has shown that people with two or more conditions of Physical health has a higher risk of depression and anxiety later in life, compared to those who do not have any or all physical condition.What is really interesting is that this risk seems to be higher in those with certain combinations of physical conditions. , which has implications for the integration of mental and physical health. should be implemented. “

Currently, more than a quarter of adults enrolled in primary care services in the UK have two or more physical health problems, known as multimorbidity, and it is expected to increase considerably in the coming years. Previous research has established a relationship between multiple physical health problems and poor mental health, but little is known about how specific patterns of physical health conditions precede the development of depression and anxiety. The study looked at data from the UK Biobank on more than 150,000 to investigate the relationship between multimorbidity of physical health measured at one point and depression and anxiety assessed four to six years later. The research took into account the influence of variables such as age, gender and socioeconomic status.

The study showed that people with three physical health conditions were almost twice as likely to develop depression later in life compared to people with one or no physical condition. The risk of future depression increases in proportion to the number of physical health conditions.

Those with various respiratory health conditions, such as asthma and emphysema, were more likely to suffer from depression later: more than triple the odds of people without physical multimorbidity. Patterns of long-term health conditions in which gastrointestinal conditions such as IBS occurred with painful conditions such as back pain or arthritis were also strong predictors of the development of depression.

The study also investigated the relationship between multimorbidity and subsequent experiences of anxiety and found similar results to depression in the fact that two or more physical health conditions increased the chances of developing anxiety later in life.

The lead author, Dr. Alexandru Dregan, of the IoPPN, said: “Finding that different patterns of physical health conditions confer different levels of risk of developing depression and anxiety later could help inform services about which patients require what type of support. it is needed to investigate the mechanisms that link different clusters to depression and anxiety, which can ultimately help us develop better approaches to better support those with long-term conditions and provide more integrated care. ”

Jayati Das-Munshi, author and psychiatrist consultant for South London and the Maudsley NHS Foundation Trust, said: “We are learning more about the links between mental and physical health and this study provides an important insight into what combinations of health conditions in long term are related to i . By using approaches that integrate physical and mental health care, we can help lessen the impact of multiple physical health problems. For example, the Mind and Body program is involved in several projects that seek to do so through Kings’ Health Partners, and one example is the IMPARTS initiative that aims to detect common mental disorders in people with physical health conditions. ”


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More information:
The Lancet Regional Health – Europe, www.thelancet.com/journals/lan … 2 (21) 00126-5 / fulltex

Citation: Several Long-Term Physical Health Problems Increase Risk of Depression Later in Life (2021, June 22) Retrieved June 22, 2021 at https://medicalxpress.com/news/2021-06-multiple- long-term-physical-health- problems.html

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