Comparative diets for mild to moderate Crohn’s disease in adults

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(HealthDay): The specific carbohydrate diet (SCD) is not superior to the Mediterranean diet (MD) for the remission of symptoms in adults with mild to moderate Crohn’s disease (CD), according to a study published online on 26 from May to Gastroenterology.

James D. Lewis, MD, of the University of Pennsylvania in Philadelphia, and his colleagues randomly assigned 194 with CD and mild-to-moderate symptoms on MD or SCD for 12 weeks.

The researchers found that the percentage of participants who achieved symptomatic remission at week 6 was not higher with SCD (SCD: 46.5%; MD: 43.5%). Eight of 23 SCD participants and four of 13 MD participants achieved a fecal response to calprotectin (CF) (50 percent among those with basal HR> 250 μg / g), while two of 37 and one of 28, respectively. , achieved a C-reactive protein response (CRP) (50% reduction in high-sensitivity CRP relative to baseline among those with high-sensitivity CRP> 5 mg / L).

“Given these results, the easier it is to follow the MD, and others associated with MD, MD may be preferred to SCD for most CD patients with mild to moderate symptoms, ”the authors write.

Several authors revealed financial links with the pharmaceutical and biopharmaceutical industries.


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Citation: Comparative Diets for Mild to Moderate Crohn’s Disease in Adults (2021, June 9) Retrieved June 9, 2021 from https://medicalxpress.com/news/2021-06-diets-mild-to- moderate-crohn-disease- adults.html

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