Beneficial bacteria can be restored in babies with cesarean section at birth

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Maria Gloria Dominguez-Bello, Professor in the Department of Biochemistry and Microbiology and Department of Anthropology at Rutgers-New Brunswick University. Credit: Jeff Heckman

Babies born by cesarean section do not have the same healthy bacteria as those born vaginally, but a study led by Rutgers first found that these natural bacteria can be restored.

The study appears in the journal With.

He it consists of billions of bacteria, viruses, fungi and other microorganisms, some beneficial and others harmful, that live in our body. Women naturally provide these pioneer colonizers to the sterile body of their babies during labor and delivery, helping their immune system to develop. But antibiotics and C-sections disrupt this passage of microbes and are related to the increased risk of obesity, asthma and .

The researchers followed 177 babies from four countries during the first year of their lives: 98 were born vaginally and 79 were born by cesarean section, 30 of whom were whipped with maternal vaginal gauze just after birth.

Laboratory analysis showed that the microbiota of section C babies rubbed with their mother’s vaginal fluids was close to that of babies born vaginally. In addition, the mother’s vaginal microbiomes on the day of birth were similar to other areas of her body (gut, mouth, and skin), showing that maternal vaginal fluids help colonize bacteria in her babies ’bodies.

This was the first major observational study that showed that restoring a baby’s natural C-section exposure to maternal vaginal microbes at birth normalizes microbiome development during its first year of life. The researchers said the next step is to perform randomly to determine whether microbiota normalization translates into disease protection.

“More research is needed to determine which bacteria protect against obesity, asthma and allergies, diseases with underlying inflammation,” said Maria Gloria Domínguez Bello, lead author, professor in the Department of Biochemistry and Microbiology of the Rutgers School of Environmental and Biological Sciences. University-New Brunswick. “Our results support the hypothesis that the acquisition of maternal vaginal microbes normalizes microbiome development in infants.”

According to the World Health Organization, cesarean delivery is necessary in approximately 15 percent of births to avoid risking the life of the mother or child, but in many countries such as Brazil, the Dominican Republic, Iran and the United States. China, section C is performed in more than 70% of urban births.


Promise babies by cesarean section with potentially unsafe and unnecessary vaginal fluids


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Citation: Beneficial Bacteria Can Be Restored to Section C Babies at Birth (2021, June 17), Retrieved June 17, 2021 at https://medicalxpress.com/news/2021-06-beneficial-bacteria-c -section-babies-birth. html

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