A new study reveals how smoking during puberty can cause negative consequences on offspring

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Credit: University of Bergen

Through a continuous analysis of data collected in three major international studies (RHINESSA, RHINE, and ECRHS), researchers have found that the health of future generations depends on the actions and decisions made by today’s youth. This is particularly relevant for boys in early puberty and mothers / grandmothers, both before and during pregnancy, according to the study.

The article “Prenatal and prepubertal exhibitions in in men may cause lower lung function in future offspring: a three-generation study using a causal modeling approach was recently published. ” European Respiratory Journal. The study highlights the importance of focusing more on smoking (defined before age 15) to prevent potential damage to lung function in future generations. He also suggests including the use of wet oral tobacco (snus) and the use of electronic cigarettes.

According to the World Health Organization (WHO), approximately 6 million people die every day from tobacco-related diseases. The number is expected to increase by more than 8 million by 2030. The UiB study stresses that smokers not only endanger their , but also the health of their children and possibly their grandchildren.

Changes in male germ cells

The study finds that both the prenatal period and the pre-puberty period are times of high importance for cell growth, particularly germ cells. Researchers suggest that lifestyle and impact on respiratory health by epigenetic changes transmitted through male germ cells. In addition, the study finds that lifestyle-related exposures during these periods influence the health of future generations.

In addition to reducing lung function, the RHINESSA study finds that prepubertal smoking in children can cause obesity in their children. However, interventions aimed at preventing smoking (nicotine use) in the most vulnerable time windows can have potential benefits for several generations.


Exposure of second-hand tobacco in the uterus related to decreased lung function in children


More information:
Simone Accordini et al. Prenatal and prepubertal exposures to tobacco smoke in men may cause inferior lung function in future offspring: a three-generation study using a causal modeling approach, European Respiratory Journal (2021). DOI: 10.1183 / 13993003.02791-2020

Citation: New study reveals how smoking during puberty can cause negative consequences for offspring (2021, May 31) recovered on May 31, 2021 at https://medicalxpress.com/news/2021-05-reveal-puberty- negative-consequences-offspring.html

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